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Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Charles River Laboratories provides preclinical, safety assessment and laboratory services to pharmaceutical, biotech and academic customers worldwide, supporting early-stage drug discovery through nonclinical and clinical work. Long-term growth may be supported by secular R&D outsourcing and rising biologics and cell/gene therapy development, and investors may find the company attractive for its scale, diversified services and global network.
Major risks include regulatory and reputational pressure around animal testing, sensitivity to pharmaceutical R&D cycles, competitive and pricing pressure, and execution and leverage risks from acquisitions.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -99.50M | 93.11M | 581.28M | 622.99M | 480.71M |
| Minority interest | -2.17M | -3.09M | -5.57M | 6.38M | 7.86M |
| Net income | -144.34M | 10.30M | 474.62M | 486.23M | 390.98M |
| Selling general administrative | 723.42M | 751.00M | 750.35M | 665.10M | 619.92M |
| Gross profit | 1225.57M | 1331.82M | 1502.56M | 1462.65M | 1334.64M |
| Reconciled depreciation | 403.31M | 361.74M | 311.15M | 303.87M | 265.54M |
| Ebit | 507.84M | 219.40M | 717.99M | 650.98M | 589.86M |
| Ebitda | 911.15M | 581.14M | 1032.12M | 986.15M | 820.16M |
| Depreciation and amortization | 403.31M | 361.74M | 314.12M | 335.17M | 230.30M |
| Non operating income net other | - | - | - | 31.30M | -35.24M |
| Operating income | 507.84M | 227.35M | 617.26M | 650.98M | 589.86M |
| Other operating expenses | 3507.54M | 3822.64M | 3512.15M | 3325.09M | 2950.30M |
| Interest expense | 107.03M | 126.29M | 136.71M | 59.29M | 73.91M |
| Tax provision | 42.66M | 67.82M | 136.97M | 130.38M | 81.87M |
| Interest income | 126.99M | 8.57M | 3.95M | 0.78M | 74.86M |
| Net interest income | -102.09M | -117.71M | -134.00M | -58.51M | -73.26M |
| Income tax expense | 42.66M | 67.82M | 100.91M | 130.38M | 81.87M |
| Total revenue | 4015.38M | 4049.99M | 4129.41M | 3976.06M | 3540.16M |
| Total operating expenses | 717.73M | 1104.47M | 885.29M | 811.68M | 744.78M |
| Cost of revenue | 2789.81M | 2718.17M | 2626.85M | 2513.41M | 2205.52M |
| Total other income expense net | -607.34M | -134.23M | -35.98M | -27.99M | -109.15M |
| Net income from continuing ops | -142.16M | 25.29M | 480.52M | 492.61M | 398.84M |
| Net income applicable to common shares | -144.34M | 10.30M | 474.62M | 486.23M | 390.98M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 7135.42M | 7528.35M | 8195.00M | 7602.77M | 7024.29M |
| Intangible assets | 340.00M | 723.40M | 864.05M | 955.27M | 1061.19M |
| Other current assets | 224.65M | 209.01M | 171.26M | 107.58M | 97.31M |
| Total liab | 3924.23M | 4020.27M | 4536.00M | 4579.27M | 4432.30M |
| Total stockholder equity | 3164.63M | 3461.50M | 3596.88M | 2976.29M | 2534.82M |
| Deferred long term liab | - | - | - | 215.58M | 239.72M |
| Other current liab | 700.04M | 605.44M | 605.52M | 621.41M | 612.56M |
| Common stock | 0.49M | 0.51M | 0.51M | 0.51M | 0.51M |
| Capital stock | 0.49M | 0.51M | 0.51M | 0.51M | 0.51M |
| Retained earnings | 1388.62M | 1812.10M | 1887.22M | 1432.90M | 980.75M |
| Other liab | - | - | - | 390.40M | 482.58M |
| Good will | 2764.25M | 2846.61M | 3095.05M | 2849.90M | 2711.88M |
| Other assets | 360.52M | 320.41M | 349.66M | 0.00M | -47.21M |
| Cash | 213.77M | 194.61M | 276.77M | 233.91M | 241.21M |
| Cash and equivalents | 213.77M | 194.61M | 276.77M | 233.91M | 241.21M |
| Total current liabilities | 1120.32M | 994.10M | 1055.08M | 1091.59M | 1033.18M |
| Current deferred revenue | 210.42M | 248.32M | 241.82M | 264.26M | 219.70M |
| Net debt | 2851.74M | 2529.39M | 2789.61M | 2863.36M | 2678.12M |
| Short term debt | 61.06M | 114.02M | 441.12M | 0.00M | 2.79M |
| Short long term debt | - | - | - | - | 0.10M |
| Short long term debt total | 3065.51M | 2723.99M | 3066.38M | 3097.28M | 2919.33M |
| Other stockholder equity | 1947.30M | 1966.24M | 1905.58M | 1804.94M | 1718.30M |
| Property plant equipment | 2016.63M | 2016.50M | 2033.77M | 1857.42M | 1584.01M |
| Total current assets | 1447.05M | 1403.07M | 1608.66M | 1439.03M | 1274.10M |
| Long term investments | 206.97M | 218.35M | 243.81M | 311.60M | 201.35M |
| Net tangible assets | - | - | - | -786.46M | -1185.24M |
| Short term investments | - | 0.06M | 0.07M | 1.00M | 1.06M |
| Net receivables | 708.86M | 720.91M | 780.38M | 752.39M | 642.88M |
| Long term debt | 2111.71M | 2240.20M | 2647.15M | 2707.53M | 2639.03M |
| Inventory | 299.10M | 278.54M | 380.26M | 255.81M | 199.15M |
| Accounts payable | 148.80M | 140.34M | 168.94M | 205.91M | 198.13M |
| Noncontrolling interest in consolidated entity | - | - | - | 4.79M | 4.16M |
| Accumulated other comprehensive income | -171.78M | -317.35M | -196.43M | -262.06M | -164.74M |
| Common stock total equity | - | - | - | 0.51M | 0.51M |
| Retained earnings total equity | - | - | - | 1432.90M | 980.75M |
| Non currrent assets other | 293.19M | 278.23M | 309.38M | 148.28M | 151.54M |
| Non current assets total | 5688.37M | 6125.27M | 6586.34M | 6163.74M | 5750.20M |
| Capital lease obligations | 458.70M | 483.79M | 419.23M | 389.75M | 316.16M |
| Long term debt total | 2136.36M | 2240.20M | 2647.15M | 2707.53M | 2663.56M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -10.97M | -245.09M | -280.40M | -153.72M | -39.02M |
| Change to liabilities | - | - | - | -44.82M | 89.20M |
| Total cashflows from investing activities | -209.32M | -245.09M | -563.15M | -607.92M | -1437.93M |
| Net borrowings | -121.78M | -412.19M | -75.32M | 19.79M | 669.98M |
| Total cash from financing activities | -536.73M | -550.93M | -85.52M | -42.40M | 672.60M |
| Change to operating activities | - | - | - | -8.92M | 46.31M |
| Net income | -142.16M | 25.29M | 480.37M | 492.61M | 398.84M |
| Change in cash | 10.43M | -78.91M | 43.27M | -5.10M | 13.20M |
| Begin period cash flow | 205.57M | 284.48M | 241.21M | 246.31M | 233.12M |
| End period cash flow | 216.00M | 205.57M | 284.48M | 241.21M | 246.31M |
| Total cash from operating activities | 737.65M | 734.58M | 683.90M | 619.64M | 760.80M |
| Depreciation | 403.31M | 361.74M | 314.12M | 303.87M | 265.54M |
| Other cashflows from investing activities | 20.80M | 4.55M | -2.29M | -129.46M | -1170.14M |
| Dividends paid | - | - | 25.60M | - | - |
| Change to inventory | -48.78M | 16.80M | -62.30M | -78.52M | -25.16M |
| Change to account receivables | 35.74M | 21.61M | -33.43M | -150.57M | -26.63M |
| Sale purchase of stock | -360.67M | -119.17M | -24.16M | -38.65M | -40.71M |
| Other cashflows from financing activities | -54.98M | -19.56M | 13.96M | 2903.78M | 6956.18M |
| Change to netincome | - | - | - | -51.06M | 23.06M |
| Capital expenditures | 219.15M | 232.97M | 318.53M | 324.73M | 228.77M |
| Change receivables | - | - | - | -150.57M | -26.63M |
| Cash flows other operating | - | - | - | 148.13M | 35.95M |
| Cash and cash equivalents changes | - | - | - | -30.68M | -4.54M |
| Change in working capital | 14.08M | -30.33M | -102.38M | -152.55M | 42.94M |
| Stock based compensation | 71.08M | 69.89M | 72.05M | 73.62M | 71.47M |
| Other non cash items | 466.62M | 375.41M | -29.36M | -62.02M | 6.01M |
| Free cash flow | 518.49M | 501.61M | 365.37M | 294.91M | 532.03M |
Sector: Healthcare Industry: Diagnostics & Research
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| CRL Charles River Laboratories |
- -% |
342.69 | - | 16.47 | 2.25 | 2.85 | 2.84 | 27.73 |
| TMO Thermo Fisher Scientific Inc |
-0.49 0.07% |
717.71 | 34.71 | 23.87 | 4.62 | 4.43 | 5.29 | 20.89 |
| DHR Danaher Corporation |
-0.80 0.34% |
235.31 | 29.09 | 28.01 | 5.67 | 3.20 | 6.00 | 19.09 |
| WUXIF WuXi AppTec Co. Ltd |
- -% |
25.84 | 22.29 | 17.95 | 1.53 | 5.98 | 8.39 | 14.30 |
| WUXAY WuXi AppTec Co. Ltd |
-0.50 1.94% |
25.10 | 23.28 | 18.73 | 1.51 | 6.24 | 8.39 | 14.30 |
Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.
251 Ballardvale Street, Wilmington, MA, United States, 01887
781 222 6000
18300
| Name | Title | Year Born |
|---|---|---|
| Mr. James C. Foster J.D. | Chairman, CEO & Pres | 1951 |
| Ms. Birgit Girshick | Corp. Exec. VP & COO | 1970 |
| Mr. Joseph W. LaPlume | Corp. Exec. VP of Corp. Devel. & Strategy | 1974 |
| Mr. William D. Barbo | Chief Commercial Officer & Corp. Exec. VP | 1961 |
| Mr. David Ross Smith | Sr. Financial Advisor | 1966 |
| Ms. Flavia H. Pease | Corp. Exec. VP & CFO | NA |
| Mr. Michael Gunnar Knell | Corp. Sr. VP & Chief Accounting Officer | 1977 |
| Prof. Julie Frearson Ph.D. | Corp. Sr. VP & Chief Scientific Officer | NA |
| Mr. Mark Mintz | Corp. Sr. VP & Chief Information Officer | NA |
| Todd Spencer | Corp. VP of Investor Relations | NA |
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