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Entropy Neurodynamics Limited, a clinical-stage pharmaceutical development company, focuses on developing formulations for the administration of psilocin in combination with psychotherapy to treat diseases with unmet medical needs in Australia, Canada, Switzerland, and the United States. The company's lead program candidate is TRP-8803, a formulation of IV-infused psilocin that completed Phase 2 clinical trial for the treatment of binge eating disorder, fibromyalgia, irritable bowel syndrome, abdominal pain, and visceral tenderness. It is also involved in the development of TRP-8802, a synthetic and oral psilocybin currently under phase 2a clinical trial for the treatment of binge eating, as well as under phase 2 clinical stage for the treatment of fibromyalgia and irritable bowel syndrome. In addition, it is pursuing Phase 2 clinical trials using its psilocybin and psilocin-based drug products for chronic pain and eating disorders. The company was formerly known as Tryptamine Therapeutics Limited and changed its name to Entropy Neurodynamics Limited in November 2025. Entropy Neurodynamics Limited was founded in 2019 and is based in Hawthorn East, Australia.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Entropy Neurodynamics Limited (ASX:ENP) has limited public disclosure; it appears to be an Australian company focused on neurotechnology research and development. Long-term growth drivers could include expanding clinical applications for neuromodulation, demographic trends increasing neurological disease prevalence, and technological advances that may support commercialisation, which may attract investors seeking early-stage exposure to neuroscience innovation.
Principal investment risks include clinical and regulatory uncertainty typical of neurotechnology ventures, execution and intellectual property challenges, and dependence on external financing that may dilute shareholders.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Income before tax | -6.78M | -6.91M | -7.25M | -7.13M | -10.08M |
| Net income | -4.87M | -5.33M | -6.14M | -7.13M | -10.08M |
| Selling general administrative | - | 4.28M | 3.00M | 6.41M | 9.39M |
| Selling and marketing expenses | - | - | - | 0.09M | 0.29M |
| Gross profit | -0.03M | -0.05M | -0.01M | 0.62M | 0.10M |
| Ebit | -6.77M | -5.32M | -6.71M | -6.80M | -10.00M |
| Ebitda | -6.74M | -5.27M | -6.70M | -5.10M | -8.27M |
| Depreciation and amortization | 0.03M | 0.05M | 0.01M | 1.70M | 1.73M |
| Operating income | -6.77M | -6.73M | -4.97M | -9.59M | -14.11M |
| Other operating expenses | 6.77M | 6.73M | 4.97M | 10.21M | 14.21M |
| Interest expense | - | 0.01M | 0.54M | 0.33M | 0.08M |
| Tax provision | - | 0.00M | 0.00M | 0.00M | - |
| Interest income | - | -0.05M | -0.54M | - | - |
| Income tax expense | -1.91M | -1.58M | -1.11M | - | -4.06M |
| Total revenue | - | 1.59M | 1.12M | 0.62M | 0.10M |
| Total operating expenses | 6.74M | 6.68M | 4.96M | 10.21M | 14.21M |
| Cost of revenue | 0.03M | 0.05M | 0.01M | - | - |
| Total other income expense net | -0.01M | -0.18M | -2.28M | 2.46M | 4.03M |
| Net income applicable to common shares | - | -5.33M | -6.14M | -7.13M | - |
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Total assets | 8.38M | 6.66M | 7.45M | 5.88M | 13.61M |
| Intangible assets | 0.18M | 0.20M | 0.37M | 0.28M | 0.33M |
| Other current assets | 0.44M | 0.56M | 0.31M | 2.88M | 4.48M |
| Total liab | 1.02M | 0.70M | 1.83M | 1.75M | 4.81M |
| Total stockholder equity | 7.36M | 5.96M | 5.62M | 4.13M | 8.81M |
| Other current liab | 0.80M | 0.48M | 0.56M | 0.14M | 0.81M |
| Common stock | 41.11M | 35.31M | 29.91M | 36.73M | 34.31M |
| Retained earnings | -40.27M | -35.41M | -30.07M | -33.42M | -26.29M |
| Other assets | - | 0.00M | 0.00M | 0.00M | - |
| Cash | 5.58M | 3.03M | 5.37M | 1.64M | 4.85M |
| Cash and equivalents | - | 3.03M | 5.37M | - | - |
| Total current liabilities | 1.02M | 0.70M | 1.83M | 1.71M | 4.46M |
| Net debt | -5.58M | -3.03M | -5.37M | -0.11M | -1.10M |
| Short term debt | - | 0.00M | 0.00M | 1.53M | 3.44M |
| Short long term debt total | - | - | - | 1.53M | 3.74M |
| Property plant equipment | - | 0.11M | - | 1.01M | - |
| Total current assets | 8.11M | 6.35M | 7.08M | 4.59M | 9.46M |
| Net receivables | 2.09M | 2.76M | 1.40M | 0.07M | 0.13M |
| Long term debt | - | - | 0.00M | - | - |
| Accounts payable | 0.22M | 0.22M | 1.27M | 0.04M | 0.21M |
| Accumulated other comprehensive income | 6.53M | 6.06M | 5.78M | 0.82M | 0.78M |
| Non currrent assets other | 0.00M | - | 0.00M | - | 0.58M |
| Non current assets total | 0.28M | 0.31M | 0.37M | 1.30M | 4.15M |
| Long term debt total | - | 0.00M | 0.00M | 0.00M | - |
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Total cashflows from investing activities | -0.01M | -0.13M | 1.68M | -0.01M | -1.24M |
| Total cash from financing activities | 5.97M | 5.60M | 9.27M | 2.39M | 1.95M |
| Net income | -4.87M | -5.33M | -6.14M | -5.85M | -10.08M |
| Change in cash | 2.55M | -2.34M | 4.93M | -3.20M | -7.88M |
| Begin period cash flow | 3.03M | 5.33M | 0.44M | 4.85M | 12.72M |
| End period cash flow | 5.58M | 3.03M | 5.37M | 1.64M | 4.85M |
| Total cash from operating activities | -3.41M | -7.77M | -6.00M | -4.03M | -8.59M |
| Depreciation | 0.03M | 0.05M | 0.01M | - | 1.73M |
| Other cashflows from investing activities | - | -0.00M | 1.68M | 0.28M | -0.11M |
| Sale purchase of stock | - | -0.40M | 6.50M | - | - |
| Other cashflows from financing activities | - | -0.40M | -0.62M | 1.15M | -0.78M |
| Capital expenditures | 0.01M | 0.13M | 0.00M | 0.00M | 1.13M |
| Change in working capital | 1.12M | -2.70M | -2.40M | 1.20M | 6.60M |
| Other non cash items | 0.32M | 0.21M | 2.53M | 0.63M | -6.84M |
| Free cash flow | -3.41M | -7.90M | -6.00M | -4.03M | -9.72M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(AUD) |
Price
(AUD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| ENP Entropy Neurodynamics Limited |
- -% |
0.03 | - | - | 24.86 | 6.21 | 18.22 | -0.27 |
| CSL CSL Ltd |
2.86 1.42% |
204.54 | - | 22.57 | 6.15 | 4.48 | 4.82 | 10.06 |
| TLX TELIX Pharmaceuticals Ltd |
-0.32 2.28% |
13.70 | 93.87 | 166.67 | 5.37 | 6.37 | 3.85 | 47.29 |
| NEU Neuren Pharmaceuticals Ltd |
-0.30 1.25% |
23.66 | 154.93 | 36.36 | 42.38 | 7.52 | 31.95 | 160.40 |
| MSB Mesoblast Ltd |
-0.07 3.69% |
1.96 | - | 454.55 | 23.43 | 3.36 | 18.28 | -9.86 |
Entropy Neurodynamics Limited, a clinical-stage pharmaceutical development company, focuses on developing formulations for the administration of psilocin in combination with psychotherapy to treat diseases with unmet medical needs in Australia, Canada, Switzerland, and the United States. The company's lead program candidate is TRP-8803, a formulation of IV-infused psilocin that completed Phase 2 clinical trial for the treatment of binge eating disorder, fibromyalgia, irritable bowel syndrome, abdominal pain, and visceral tenderness. It is also involved in the development of TRP-8802, a synthetic and oral psilocybin currently under phase 2a clinical trial for the treatment of binge eating, as well as under phase 2 clinical stage for the treatment of fibromyalgia and irritable bowel syndrome. In addition, it is pursuing Phase 2 clinical trials using its psilocybin and psilocin-based drug products for chronic pain and eating disorders. The company was formerly known as Tryptamine Therapeutics Limited and changed its name to Entropy Neurodynamics Limited in November 2025. Entropy Neurodynamics Limited was founded in 2019 and is based in Hawthorn East, Australia.
Bio101 Financial Advisory Pty Ltd, Hawthorn East, VIC, Australia, 3123
61 3 9092 0475
| Name | Title | Year Born |
|---|---|---|
| Mr. Jason Alan Carroll | MD, CEO & Executive Director | NA |
| Dr. James P. Gilligan MSIB, Ph.D. | President & Chief Scientific Officer | 1952 |
| Mr. Christopher Leo Ntoumenopoulos | Executive Director | 1983 |
| Mr. Hamish George B.Com., C.A. | CFO & Company Secretary | NA |
| Dr. Michael H. Silverman B.Sc., F.A.C.P., FACR, M.B.A., M.D. | Chief Medical Officer | 1948 |
| Mr. Christopher Leo Ntoumenopoulos | Executive Director | 1984 |
| Dr. Michael H. Silverman B.Sc., F.A.C.P., FACR, M.B.A., M.D. | Chief Medical Officer | 1949 |
| Ms. Meghna Piplani | Joint Company Secretary | NA |
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