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Atrium Therapeutics, Inc., a biopharmaceutical company, focuses on delivering ribonucleic acid (RNA) therapeutics to the heart to transform the care for people living with cardiomyopathies. The company's development stage product candidates include ATR 1072, a siRNA-based therapy targeting PRKAG2 for the treatment of PRKAG2 syndrome; and ATR 1086, a siRNA-based therapy targeting PLN for the treatment of PLN cardiomyopathy. It also focuses on pipeline to treat a range of genetic and cardiac diseases. It has a research collaboration and license agreement with Bristol-Myers Squibb Company and Eli Lilly and Company. The company was incorporated in 2025 and is headquartered in San Diego, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Public information on Atrium Therapeutics, Inc. (NASDAQ: RNA) is limited; available filings and disclosures characterize it as an early-stage biopharmaceutical company developing therapeutic candidates for serious or rare diseases. Long-term growth may depend on successful clinical development, regulatory approvals, and strategic partnerships, and investors may find potential upside if the company advances programs that address unmet medical needs.
Material risks include clinical and regulatory failure, substantial funding and dilution risk from ongoing capital needs, an unproven operating history with no predictable revenues, and limited public disclosure that increases uncertainty for investors.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -76.83M | -322.30M | -212.22M | -174.00M | -118.01M |
| Net income | -76.68M | -322.30M | -212.22M | -169.08M | -117.37M |
| Selling general administrative | 41.68M | 86.24M | 54.19M | 37.73M | 26.20M |
| Selling and marketing expenses | - | - | 2.10M | - | - |
| Gross profit | 18.62M | 10.90M | 7.46M | 9.22M | 9.33M |
| Reconciled depreciation | 0.32M | 2.78M | 1.87M | 1.39M | 0.64M |
| Ebit | -76.83M | -378.94M | -235.60M | -180.30M | -118.69M |
| Ebitda | -76.50M | -376.16M | -233.50M | -178.91M | -118.05M |
| Depreciation and amortization | 0.32M | 2.78M | 2.10M | 1.39M | 0.64M |
| Operating income | -76.81M | -378.94M | -235.60M | -178.91M | -118.05M |
| Other operating expenses | 95.43M | 389.83M | 245.16M | 188.14M | 127.38M |
| Interest expense | - | - | - | 5.69M | 0.64M |
| Tax provision | -0.14M | 11.91M | 0.00M | - | - |
| Interest income | - | 56.88M | 20.34M | 4.97M | 0.10M |
| Net interest income | - | 56.88M | 20.34M | 4.97M | 0.10M |
| Income tax expense | -0.14M | - | 1.93M | -4.92M | -0.64M |
| Total revenue | 18.62M | 10.90M | 9.56M | 9.22M | 9.33M |
| Total operating expenses | 95.43M | 389.83M | 243.06M | 188.14M | 127.38M |
| Cost of revenue | 4.15M | 2.78M | 2.10M | - | - |
| Total other income expense net | -0.01M | 56.63M | 23.38M | 4.92M | 0.04M |
| Net income from continuing ops | -76.68M | -322.30M | -202.25M | -174.00M | -118.01M |
| Net income applicable to common shares | - | - | - | -174.00M | -118.01M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 278.35M | 1563.89M | 628.55M | 638.80M | 427.58M |
| Other current assets | 2.85M | 12.57M | 14.05M | 12.21M | 5.60M |
| Total liab | 71.07M | 138.94M | 127.79M | 60.73M | 46.15M |
| Total stockholder equity | 207.29M | 1424.96M | 500.76M | 578.08M | 381.43M |
| Other current liab | 12.09M | 64.73M | 39.87M | 39.12M | 23.02M |
| Common stock | 0.02M | 0.01M | 0.01M | 0.01M | 0.01M |
| Capital stock | 0.02M | 0.01M | 0.01M | 0.01M | 0.01M |
| Retained earnings | -1577.70M | -893.07M | -570.76M | -358.54M | -184.55M |
| Other liab | - | - | - | 1.24M | 6.53M |
| Other assets | - | - | 0.00M | 0.85M | 0.85M |
| Cash | 270.00M | 219.87M | 185.08M | 340.40M | 405.54M |
| Total current liabilities | 41.80M | 98.02M | 80.68M | 51.91M | 29.66M |
| Current deferred revenue | 21.64M | 20.99M | 28.36M | 5.04M | 4.86M |
| Net debt | -266.33M | -213.07M | -175.23M | -329.71M | -395.58M |
| Short term debt | 3.67M | 3.84M | 3.64M | 3.10M | 1.77M |
| Short long term debt total | 3.67M | 6.80M | 9.85M | 10.69M | 9.96M |
| Other stockholder equity | 207.27M | 2315.11M | 1071.39M | 939.31M | 566.16M |
| Property plant equipment | - | - | - | 15.01M | 15.59M |
| Total current assets | 272.85M | 1542.29M | 611.31M | 622.94M | 411.14M |
| Net tangible assets | - | - | - | 578.08M | 381.43M |
| Short term investments | 1314.35M | 1281.63M | 410.27M | 270.33M | 85.09M |
| Net receivables | 12.44M | 28.22M | 1.91M | 2.10M | 0.90M |
| Accounts payable | 4.40M | 8.46M | 8.81M | 4.64M | 14.09M |
| Accumulated other comprehensive income | 2.56M | 2.90M | 0.12M | -2.70M | -0.19M |
| Non currrent assets other | 84.97M | 3.32M | 0.30M | 0.85M | 0.85M |
| Non current assets total | 5.51M | 21.61M | 17.25M | 15.86M | 16.44M |
| Capital lease obligations | 3.67M | 6.80M | 9.85M | 7.58M | 11.73M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | -854.20M | -188.88M | -189.96M | -78.78M |
| Change to liabilities | - | - | - | 13.20M | 1.60M |
| Total cashflows from investing activities | -1.45M | -854.20M | -130.07M | -189.96M | -82.52M |
| Total cash from financing activities | 42.57M | 1192.36M | 93.86M | 346.17M | 176.32M |
| Change to operating activities | - | - | - | -3.38M | 3.74M |
| Net income | -49.50M | -322.30M | -212.22M | -174.00M | -118.01M |
| Change in cash | 162.65M | 37.29M | -155.27M | 19.95M | -1.01M |
| Begin period cash flow | 222.66M | 185.38M | 340.65M | 320.70M | 321.71M |
| End period cash flow | 385.31M | 222.66M | 185.38M | 340.65M | 320.70M |
| Total cash from operating activities | -41.13M | -300.87M | -119.06M | -136.27M | -94.81M |
| Issuance of capital stock | - | 1000.55M | 303.62M | 344.78M | 185.94M |
| Depreciation | 0.32M | 2.78M | 2.10M | 1.39M | 0.64M |
| Other cashflows from investing activities | -4.07M | - | - | - | - |
| Dividends paid | - | - | - | - | 0.00M |
| Change to account receivables | 0.00M | 0.75M | 1.39M | - | - |
| Other cashflows from financing activities | 42.57M | 191.81M | 33.32M | 1.39M | -9.62M |
| Change to netincome | - | - | - | 26.52M | 17.22M |
| Capital expenditures | 1.45M | 7.07M | 4.23M | 2.82M | 3.74M |
| Change in working capital | -0.20M | -14.56M | 61.13M | 9.82M | 5.34M |
| Stock based compensation | 7.68M | 51.36M | 38.22M | 27.14M | 17.06M |
| Other non cash items | 0.71M | -18.15M | -8.30M | -0.61M | 0.16M |
| Free cash flow | -42.57M | -307.94M | -123.29M | -139.09M | -98.55M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| RNA Atrium Therapeutics, Inc. Common Stock |
-0.27 3.28% |
7.96 | - | - | 4.82 | 0.80 | 491.01 | -5.72 |
| NVO Novo Nordisk A/S |
0.41 1.00% |
41.10 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-0.86 0.16% |
547.03 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
43.35 4.73% |
959.41 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Atrium Therapeutics, Inc., a biopharmaceutical company, focuses on delivering ribonucleic acid (RNA) therapeutics to the heart to transform the care for people living with cardiomyopathies. The company's development stage product candidates include ATR 1072, a siRNA-based therapy targeting PRKAG2 for the treatment of PRKAG2 syndrome; and ATR 1086, a siRNA-based therapy targeting PLN for the treatment of PLN cardiomyopathy. It also focuses on pipeline to treat a range of genetic and cardiac diseases. It has a research collaboration and license agreement with Bristol-Myers Squibb Company and Eli Lilly and Company. The company was incorporated in 2025 and is headquartered in San Diego, California.
10578 Science Center Drive, San Diego, CA, United States, 92121
619 876 0700
511
| Name | Title | Year Born |
|---|---|---|
| Dr. Troy Edward Wilson J.D., Ph.D. | Co-Founder & Chairman | 1969 |
| Ms. Sarah Boyce | Pres, CEO & Director | 1972 |
| Mr. Michael F. MacLean | Chief Financial & Bus. Officer | 1966 |
| Dr. W. Michael Flanagan Ph.D. | Chief Technical Officer | 1962 |
| Dr. Arthur A. Levin Ph.D. | Chief Scientific Officer | 1954 |
| Prof. Mark E. Davis | Scientific Founder, Member of Scientific Advisory Board and Member of Board of Mang.s | NA |
| Dr. Frank McCormick Ph.D. | Scientific Founder & Member of Scientific Advisory Board | 1950 |
| Ms. Kathleen Gallagher | Sr. VP of Corp. Communications & Investor Relations | NA |
| Dr. John W. Wallen III | VP of Intellectual Property, Gen. Counsel & Sec. | 1958 |
| Ms. Teresa McCarthy | Chief HR Officer | NA |
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