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Kiora Pharmaceuticals, Inc., a clinical-stage specialty pharmaceutical company, engages in the development and commercialization of therapies for the treatment of ophthalmic diseases. Its lead product is KIO-301, a potential vision-restoring small molecule, which is in Phase 2 clinical trials for the treatment of retinitis pigmentosa, choroideremia, and Stargardt disease. The company is also developing KIO-104, a non-steroidal, immuno-modulatory, small-molecule inhibitor of dihydroorotate dehydrogenase, which is in phase 1b/2a study for the treatment of posterior non-infectious uveitis, as well as under pre-clinical development for the treatment of proliferative vitreoretinopathy; and KIO-101, an eye drop formulation for the treatment of ocular presentation of rheumatoid arthritis. It has a strategic development and commercialization agreement with Théa Open Innovation for the development of KIO-301. The company operates in the United States, Austria, and Australia. The company was formerly known as Eyegate Pharmaceuticals, Inc. and changed its name to Kiora Pharmaceuticals, Inc. in November 2021. Kiora Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Encinitas, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Kiora Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapies for ocular surface diseases, including severe dry eye and corneal disorders. Long-term growth may be driven by successful clinical progress, regulatory approvals, and potential collaborations to support commercialization, and investors may find the company attractive for its focused pipeline addressing unmet needs in ophthalmology with upside tied to milestone execution.
Material risks include reliance on positive clinical trial results, regulatory uncertainty, a limited cash runway likely requiring additional financing, and competition from larger ophthalmology and biotechnology firms.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -12.12M | 5.66M | -12.42M | -13.70M | -16.70M |
| Net income | -10.84M | 3.59M | -12.51M | -13.58M | -16.39M |
| Selling general administrative | 5.75M | 5.54M | 4.66M | 8.28M | 5.32M |
| Selling and marketing expenses | - | - | 0.06M | - | - |
| Gross profit | -0.02M | 16.00M | -4.03M | - | - |
| Reconciled depreciation | 0.02M | 0.02M | 0.05M | 0.04M | 0.05M |
| Ebit | -12.10M | 5.68M | -12.41M | -12.31M | -16.94M |
| Ebitda | -12.07M | 5.70M | -12.36M | -11.63M | -10.63M |
| Depreciation and amortization | 0.02M | 0.02M | 0.05M | 0.68M | 6.31M |
| Operating income | -9.46M | 4.51M | -12.59M | -12.31M | -16.94M |
| Other operating expenses | 9.46M | 11.49M | 12.59M | 11.73M | 10.67M |
| Interest expense | 0.02M | 0.02M | 0.01M | 0.01M | 0.01M |
| Tax provision | -1.28M | 2.07M | 0.09M | -0.11M | -0.30M |
| Interest income | 0.89M | 1.25M | 0.18M | 0.06M | 0.00M |
| Net interest income | 0.87M | 1.23M | 0.17M | 0.05M | -0.01M |
| Income tax expense | -1.28M | 2.07M | 0.09M | -0.11M | -0.30M |
| Total revenue | 0.00M | 16.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 9.43M | 11.49M | 12.59M | 11.73M | 10.67M |
| Cost of revenue | 0.02M | 0.38M | 4.03M | - | - |
| Total other income expense net | -2.66M | 1.15M | 0.16M | -1.39M | 0.24M |
| Net income from continuing ops | -10.84M | 3.59M | -12.74M | -13.58M | -16.39M |
| Net income applicable to common shares | - | - | - | - | -16.39M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 24.25M | 36.48M | 13.71M | 18.68M | 18.06M |
| Intangible assets | 2.06M | 6.69M | 8.81M | 10.74M | 8.70M |
| Other current assets | 1.34M | 2.31M | 0.23M | 0.34M | 0.61M |
| Total liab | 8.13M | 10.72M | 7.60M | 7.27M | 8.83M |
| Total stockholder equity | 16.13M | 25.76M | 6.11M | 11.41M | 9.22M |
| Deferred long term liab | - | - | - | - | 8.53M |
| Other current liab | 1.16M | 5.57M | 1.38M | 2.16M | 1.33M |
| Common stock | 0.28M | 0.27M | 0.08M | 0.02M | 0.13M |
| Capital stock | 0.28M | 0.27M | 0.08M | 0.02M | 0.13M |
| Retained earnings | -154.22M | -143.38M | -146.98M | -134.46M | -124.73M |
| Other liab | - | - | - | - | 7.13M |
| Good will | - | - | - | - | 0.00M |
| Other assets | - | - | 0.00M | - | 8.62M |
| Cash | 8.70M | 3.79M | 2.45M | 5.96M | 7.85M |
| Total current liabilities | 3.63M | 6.01M | 1.63M | 3.27M | 1.61M |
| Current deferred revenue | 1.25M | - | - | - | - |
| Net debt | -8.33M | -3.74M | -2.35M | -5.86M | -7.65M |
| Short term debt | 0.16M | 0.02M | 0.05M | 0.11M | 0.12M |
| Short long term debt total | 0.37M | 0.06M | 0.11M | 0.11M | 0.21M |
| Other stockholder equity | 170.31M | 169.16M | 153.19M | 146.04M | 133.92M |
| Property plant equipment | - | - | - | - | 0.28M |
| Total current assets | 21.75M | 29.71M | 4.74M | 7.68M | 8.99M |
| Net tangible assets | - | - | - | - | 9.06M |
| Short term investments | 8.39M | 23.00M | - | - | - |
| Net receivables | 3.32M | 0.60M | 2.05M | 1.37M | 0.53M |
| Inventory | - | - | 0.00M | - | - |
| Accounts payable | 1.06M | 0.42M | 0.21M | 1.01M | 0.16M |
| Accumulated other comprehensive income | -0.25M | -0.28M | -0.18M | -0.18M | -0.09M |
| Non currrent assets other | 0.06M | 0.02M | 0.04M | 0.08M | 0.09M |
| Non current assets total | 2.50M | 6.78M | 8.97M | 11.00M | 9.07M |
| Capital lease obligations | 0.37M | 0.06M | 0.11M | 0.11M | 0.21M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 14.54M | -22.66M | 0.00M | 0.01M | -0.16M |
| Change to liabilities | - | - | - | - | -0.75M |
| Total cashflows from investing activities | 14.43M | -22.66M | - | - | -0.16M |
| Net borrowings | 0.00M | 0.00M | - | - | -0.21M |
| Total cash from financing activities | 0.27M | 15.50M | 5.97M | 8.62M | 17.80M |
| Change to operating activities | - | - | - | - | -0.28M |
| Net income | -10.84M | 3.59M | -12.51M | -13.58M | -16.39M |
| Change in cash | 4.90M | 1.34M | -3.55M | -1.89M | 6.67M |
| Begin period cash flow | 3.80M | 2.46M | 6.01M | 7.90M | 1.23M |
| End period cash flow | 8.70M | 3.80M | 2.46M | 6.01M | 7.90M |
| Total cash from operating activities | -9.96M | 8.56M | -9.56M | -10.43M | -10.89M |
| Issuance of capital stock | 0.00M | 15.00M | 6.46M | 5.38M | 18.75M |
| Depreciation | 0.02M | 0.02M | 0.05M | 0.04M | 0.05M |
| Change to account receivables | -2.41M | 1.03M | -0.55M | - | - |
| Sale purchase of stock | - | - | 0.00M | -0.02M | - |
| Other cashflows from financing activities | 0.27M | 0.50M | -1.00M | 3.26M | -0.95M |
| Change to netincome | - | - | - | - | 6.32M |
| Capital expenditures | 0.11M | 0.01M | 0.00M | 0.00M | 0.06M |
| Change in working capital | -3.27M | 3.67M | -1.82M | 0.67M | -1.04M |
| Stock based compensation | 0.90M | 0.66M | 0.75M | 0.46M | 0.84M |
| Other non cash items | 3.61M | 0.91M | 3.88M | 2.10M | 5.96M |
| Free cash flow | -10.07M | 8.55M | -9.56M | -10.43M | -10.95M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| KPRX Kiora Pharmaceuticals Inc |
-0.01 0.74% |
1.34 | - | 2.41 | 0.14 | 0.70 | 13.31 | -1.03 |
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Kiora Pharmaceuticals, Inc., a clinical-stage specialty pharmaceutical company, engages in the development and commercialization of therapies for the treatment of ophthalmic diseases. Its lead product is KIO-301, a potential vision-restoring small molecule, which is in Phase 2 clinical trials for the treatment of retinitis pigmentosa, choroideremia, and Stargardt disease. The company is also developing KIO-104, a non-steroidal, immuno-modulatory, small-molecule inhibitor of dihydroorotate dehydrogenase, which is in phase 1b/2a study for the treatment of posterior non-infectious uveitis, as well as under pre-clinical development for the treatment of proliferative vitreoretinopathy; and KIO-101, an eye drop formulation for the treatment of ocular presentation of rheumatoid arthritis. It has a strategic development and commercialization agreement with Théa Open Innovation for the development of KIO-301. The company operates in the United States, Austria, and Australia. The company was formerly known as Eyegate Pharmaceuticals, Inc. and changed its name to Kiora Pharmaceuticals, Inc. in November 2021. Kiora Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Encinitas, California.
332 Encinitas Boulevard, Encinitas, CA, United States, 92024
858 224 9600
13
| Name | Title | Year Born |
|---|---|---|
| Dr. Brian M. Strem Ph.D. | Pres, CEO, Principal Financial & Accounting Officer and Director | 1979 |
| Dr. Eric J. Daniels M.B.A., M.D. | Chief Devel. Officer | 1973 |
| Dr. Stefan Sperl Ph.D. | Exec. VP of CMC & Operations | NA |
| Ms. Melissa Tosca | Exec. VP of Fin. | NA |
| Dr. MaryJane Rafii Ph.D. | Consultant | NA |
| Dr. Brian M. Strem Ph.D. | President, CEO & Director | 1980 |
| Ms. Melissa Tosca CPA | Executive Vice President of Finance | 1981 |
| Dr. Eric J. Daniels M.B.A., M.D. | Chief Development Officer | 1974 |
| Dr. Stefan Sperl Ph.D. | Executive Vice President of CMC & Operations | NA |
| Ms. Melissa Tosca CPA | Chief Financial Officer | 1980 |
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