Highlights
- Mesoblast Ltd (ASX: MSB) rose 3.23% to A$2.08 on March 4, 2026.
- The stock remains down 13.39% over the past five trading sessions.
- H1 FY2026 revenue increased to US$51.3 million from US$3.2 million year-on-year.
- Ryoncil® generated US$57.0 million in gross sales during the half year.
- The company expects FY2026 Ryoncil® net revenue between US$110 million and US$120 million.
Mesoblast Limited (ASX:MSB) (Nasdaq:MESO) traded at A$2.08 as of 12:38 pm on March 4, 2026, marking a 3.23% gain for the session. The advance comes amid recent volatility, with the stock still down 13.39% over the past five days.
Half-Year Revenue Reflects Commercial Rollout
For H1 FY2026, Mesoblast reported total revenue of US$51.3 million (A$78.3 million), compared to US$3.2 million in the prior corresponding period.
The increase followed the commercial launch of Ryoncil® (remestemcel-L-rknd) in the United States. The therapy generated gross sales of US$57.0 million and revenue of US$48.7 million after gross-to-net adjustments.
Ryoncil® delivered gross profit of US$44.2 million, excluding amortization, compared with nil in the prior year period. Direct selling costs totaled US$7.7 million.
The company reported a net loss of US$40.2 million, compared with US$47.9 million in the previous corresponding period. Excluding a US$23.0 million inventory reversal recorded last year, the year-on-year improvement in net loss would have been US$30.7 million.
Cash Position and Funding Facility
Net operating cash spend for the half year was US$30.3 million. Mesoblast indicated it expects a reduction in net cash spend over the remainder of FY2026 based on projected quarterly revenue receipts.
The company ended the period with a cash balance of US$130.0 million. It also secured a US$125.0 million five-year non-dilutive credit-line facility, with a second tranche of US$50.0 million available for drawdown until June 30, 2026.
Commercial and Pipeline Developments
As part of its operational update, Mesoblast confirmed that 49 transplant centers have been onboarded for Ryoncil®, with a target of 64 centers representing 94% of U.S. transplants. Coverage by government and commercial payers extends to 280 million U.S. lives.
The company is also progressing lifecycle extension plans for Ryoncil® and advancing development of rexlemestrocel-L in chronic low back pain and chronic heart failure with low ejection fraction.
For FY2026, Mesoblast anticipates Ryoncil® net revenue in the range of US$110 million to US$120 million.
FAQs
- What was Mesoblast’s share price on March 4, 2026?
The stock traded at A$2.08, up 3.23% for the day. - How did Mesoblast perform over the past five days?
Despite the daily gain, the shares remain down 13.39% over the last five trading sessions. - What revenue did Mesoblast report for H1 FY2026?
The company reported total revenue of US$51.3 million for the half year ended December 31, 2025.






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