Immutep Limited (ASX:IMM), a clinical-stage immunotherapy company targeting cancer and autoimmune diseases, has announced that data from two clinical trials of its first-in-class MHC Class II agonist eftilagimod alfa (efti) will be presented in poster sessions at two international medical congresses in November and December 2026.

Key Points

  • Survival data from the investigator-initiated EFTISARC-NEO Phase II trial will be presented at the CTOS 2026 Annual Meeting in Seoul, South Korea, on 19 November 2026
  • Final median overall survival results from Part B of the TACTI-003 Phase IIb trial will be presented at the ESMO Immuno-Oncology & Advanced Therapies Congress 2026 in London on 14 December 2026
  • The EFTISARC-NEO presentation covers efti in combination with pembrolizumab and radiotherapy in neoadjuvant treatment of patients with resectable soft tissue sarcoma
  • The TACTI-003 Part B presentation covers efti in combination with pembrolizumab in first-line recurrent or metastatic head and neck squamous cell carcinoma in patients with a PD-L1 combined positive score of less than 1

EFTISARC-NEO Presentation at CTOS 2026 Annual Meeting

The CTOS 2026 Annual Meeting will be held from 18 to 21 November 2026 in Seoul, South Korea. Immutep's poster, titled "Disease Free Survival (DFS) in Patients with Resectable Soft Tissue Sarcoma (STS) from Eftisarc-Neo Phase II Trial of Neoadjuvant Eftilagimod Alfa (Efti), Pembrolizumab and Radiotherapy (RTH)," is scheduled for a Poster Discussion session on 19 November 2026 at 4:30 p.m. KST. The first author is Pawel Sobczuk, MD PhD, from the Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland. The trial is registered under NCT06128863.

TACTI-003 Final Results at ESMO Immuno-Oncology Congress 2026

The ESMO Immuno-Oncology & Advanced Therapies Congress 2026 will be held from 14 to 16 December 2026 in London, United Kingdom. Immutep's poster, titled "Eftilagimod Alfa and Pembrolizumab in First-Line Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma with PD-L1 CPS <1: Final Results from the TACTI-003 Study," is scheduled for a Poster Display session on 14 December 2026 at 17:30 GMT. The first author is Claus A. Kristensen, MD PhD, from Copenhagen University Hospital in Copenhagen, Denmark. The trial is registered under NCT04811027.

Company Background and Product Portfolio

Immutep is a clinical-stage biotechnology company developing novel immunotherapies for cancer and autoimmune disease. The company describes itself as a pioneer in the understanding and advancement of therapeutics related to Lymphocyte Activation Gene-3 (LAG-3). Its product portfolio harnesses LAG-3's ability to stimulate or suppress the immune response. The company is listed on both the ASX and NASDAQ under the tickers IMM and IMMP respectively. The filing states that presentation data will be made available on Immutep's Posters & Publications page following each presentation.