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Citi initiates coverage on biotech amid improving sentiment in sector
Tue 17 Jun 25, 04:57 PMProtagonist Therapeutics (PTGX) Reports Q1 Loss, Tops Revenue Estimates
Tue 06 May 25, 10:30 PMProtagonist Reports First Quarter 2025 Financial Results and Provides Corporate Update
Tue 06 May 25, 08:05 PMExploring High Growth Tech Stocks In The US Market
Wed 19 Mar 25, 05:08 PM| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -127.39300M | -125.55100M | -64.84500M | -77.87800M | -39.72300M |
| Minority interest | - | - | - | - | - |
| Net income | -123.41300M | -122.62700M | -66.15000M | -77.18700M | -38.92400M |
| Selling general administrative | 31.74M | 27.20M | 18.64M | 15.75M | 13.70M |
| Selling and marketing expenses | - | - | - | - | - |
| Gross profit | 26.58M | 27.36M | 28.63M | 0.23M | 30.93M |
| Reconciled depreciation | 3.37M | 2.77M | 2.56M | 2.50M | 0.53M |
| Ebit | -134.74200M | -125.84500M | -64.51600M | -80.52100M | -42.79600M |
| Ebitda | -131.37300M | -125.55100M | -63.66200M | -77.70900M | -42.26900M |
| Depreciation and amortization | 3.37M | 0.29M | 0.85M | 2.81M | 0.53M |
| Non operating income net other | 3.98M | 0.29M | 0.27M | 2.81M | 2.55M |
| Operating income | -131.37300M | -125.84500M | -64.51600M | -80.52100M | -42.26900M |
| Other operating expenses | 157.95M | 153.20M | 93.14M | 80.75M | 73.19M |
| Interest expense | 3.37M | 2.48M | 0.60M | 0.17M | 0.00000M |
| Tax provision | 0.00000M | 0.00000M | 1.30M | -0.69100M | -0.79900M |
| Interest income | 4.06M | 0.44M | 0.90M | 2.81M | 2.55M |
| Net interest income | 4.06M | 0.44M | 0.30M | 2.64M | 2.55M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | -3.98000M | -2.92400M | 1.30M | -0.69100M | -0.79900M |
| Total revenue | 26.58M | 27.36M | 28.63M | 0.23M | 30.93M |
| Total operating expenses | 157.95M | 153.20M | 93.14M | 80.75M | 73.19M |
| Cost of revenue | - | - | - | - | 0.00000M |
| Total other income expense net | 3.98M | 0.29M | -0.32900M | 2.64M | 2.55M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | -127.39300M | -125.55100M | -66.15000M | -77.18700M | -38.92400M |
| Net income applicable to common shares | -127.39300M | -125.55100M | -66.15000M | -77.18700M | -38.92400M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Total assets | 744.73M | 357.95M | 247.93M | 347.69M | 324.47M |
| Intangible assets | - | - | - | - | - |
| Earning assets | - | - | - | - | - |
| Other current assets | 4.24M | 13.96M | 0.04M | 0.97M | 0.31M |
| Total liab | 69.43M | 21.27M | 784.68M | 47.67M | 44.86M |
| Total stockholder equity | 675.29M | 336.68M | -536.75500M | -409.36200M | -283.81100M |
| Deferred long term liab | - | - | - | - | - |
| Other current liab | 23.69M | 19.36M | 25.02M | 38.62M | 21.23M |
| Common stock | 0.00100M | 0.00100M | - | - | - |
| Capital stock | 0.00100M | 0.00100M | 0.00000M | 0.00000M | 0.00000M |
| Retained earnings | -340.52200M | -615.71000M | -536.75500M | -409.36200M | -283.81100M |
| Other liab | - | - | - | - | 0.12M |
| Good will | - | - | - | - | - |
| Other assets | - | - | 0.23M | 0.23M | 0.45M |
| Cash | 97.25M | 186.73M | 125.74M | 123.67M | 117.36M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 47.40M | 21.27M | 31.18M | 44.02M | 40.24M |
| Current deferred revenue | 18.89M | 0.00300M | - | 1.60M | 14.48M |
| Net debt | -86.38300M | -185.58600M | -122.08800M | -117.80700M | -111.39900M |
| Short term debt | 0.51M | 1.14M | 2.52M | 2.20M | 1.46M |
| Short long term debt | - | - | - | - | - |
| Short long term debt total | 10.87M | 1.14M | 3.66M | 5.86M | 5.96M |
| Other stockholder equity | 1015.90M | 952.49M | 0.36M | 0.30M | -0.02800M |
| Property plant equipment | - | - | 1.56M | 6.73M | 1.46M |
| Total current assets | 591.64M | 355.58M | 237.35M | 340.74M | 315.61M |
| Long term investments | 140.25M | - | - | 0.00000M | 2.00M |
| Net tangible assets | - | - | 215.61M | 300.02M | 279.61M |
| Short term investments | 321.66M | 154.89M | 111.61M | 203.24M | 188.45M |
| Net receivables | 168.49M | 10.33M | 0.05M | 4.36M | 3.51M |
| Long term debt | - | - | - | - | - |
| Inventory | - | -10.33200M | -0.09400M | 8.50M | 3.98M |
| Accounts payable | 1.61M | 0.77M | 3.64M | 1.60M | 3.08M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | -0.08200M | -0.10500M | -0.35900M | -0.29900M | 0.03M |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | - | - | - | - |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | - | -536.75500M | -409.36200M | -283.81100M |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 0.23M | 0.23M | 5.95M | 0.23M | 0.45M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 153.08M | 2.37M | 10.57M | 6.96M | 8.86M |
| Capital lease obligations | 10.87M | 1.14M | 3.66M | 5.86M | 5.96M |
| Long term debt total | - | - | - | - | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 92.26M | -14.75900M | -90.49400M | -52.74300M | 2.70M |
| Change to liabilities | -11.50000M | -14.26600M | 7.74M | -1.70100M | 7.40M |
| Total cashflows from investing activities | 91.47M | -15.86000M | -90.96500M | -53.71000M | 2.21M |
| Net borrowings | 14.55M | - | 31.52M | 9.77M | 9.77M |
| Total cash from financing activities | 18.84M | 129.92M | 247.63M | 46.04M | 24.11M |
| Change to operating activities | -9.76600M | 10.21M | 3.28M | -1.99500M | 3.85M |
| Net income | -127.39300M | -125.55100M | -66.15000M | -77.18700M | -38.92400M |
| Change in cash | 2.08M | 6.07M | 84.35M | -49.22700M | -23.79600M |
| Begin period cash flow | 123.89M | 117.82M | 33.47M | 82.69M | 106.49M |
| End period cash flow | 125.97M | 123.89M | 117.82M | 33.47M | 82.69M |
| Total cash from operating activities | -108.13700M | -107.86500M | -72.48400M | -41.52700M | -49.94700M |
| Issuance of capital stock | 14.55M | 123.83M | 255.37M | 34.49M | 23.18M |
| Depreciation | 3.37M | 2.77M | 2.56M | 2.50M | 0.53M |
| Other cashflows from investing activities | - | - | - | -52.74300M | 2.70M |
| Dividends paid | - | - | - | - | - |
| Change to inventory | - | - | - | - | 3.85M |
| Change to account receivables | 1.56M | 0.86M | -0.99000M | -2.16800M | -2.77100M |
| Sale purchase of stock | 4.45M | 130.11M | 216.10M | 36.27M | 2.44M |
| Other cashflows from financing activities | 4.29M | 6.09M | 2.79M | 11.54M | 0.93M |
| Change to netincome | 24.20M | 18.10M | 8.48M | 8.36M | 6.92M |
| Capital expenditures | 0.80M | 1.10M | 0.47M | 0.97M | 0.49M |
| Change receivables | 1.56M | 0.86M | 4.33M | -2.16800M | -2.77100M |
| Cash flows other operating | 4.51M | -17.96500M | -27.71400M | 31.06M | -23.30600M |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | 2.17M | 6.20M | 84.18M | -49.20100M | -23.61900M |
| Change in working capital | -7.76600M | -3.31400M | -19.01600M | 26.14M | -18.01700M |
| Stock based compensation | 24.20M | 16.39M | 7.90M | 8.35M | 6.92M |
| Other non cash items | -0.54900M | 1.83M | 0.78M | -0.55700M | 0.21M |
| Free cash flow | -108.93200M | -108.96600M | -72.95500M | -42.49400M | -50.43300M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to Revenue (x) | Enterprise Value to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| PTGX Protagonist Therapeutics Inc |
0.39 0.40% | 97.05 | 57.04 | 26.39 | 13.27 | 4.00 | 10.56 | 72.86 |
| NVO Novo Nordisk A/S |
-1.06 2.66% | 38.72 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
- -% | 38.88 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
38.30 8.31% | 499.17 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
-9.57 1.22% | 772.03 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical trials indicated to block biological pathways targeted by marketed injectable antibody drugs; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
7707 Gateway Boulevard, Newark, CA, United States, 94560
| Name | Title | Year Born |
|---|---|---|
| Dr. Dinesh V. Patel Ph.D. | CEO, Pres, Sec. & Director | 1957 |
| Dr. David Y. Liu Ph.D. | Chief R&D Strategy Officer | 1950 |
| Dr. Suneel K. Gupta Ph.D. | Chief Devel. Officer | 1958 |
| Dr. Richard S. Shames | Clinical Advisor | 1960 |
| Mr. Asif Ali | Exec. VP & Chief Financial Officer | NA |
| Mr. Mohammad Masjedizadeh | Exec. VP & CTO | NA |
| Mr. Matthew M. Gosling | Exec. VP & Gen. Counsel | 1971 |
| Ms. Carena Spivey | Exec. Director of HR | NA |
| Dr. Ashok Bhandari Ph.D. | Sr. VP of Discovery Chemistry & Process Research | 1964 |
| Dr. Scott Eric Plevy M.D. | Exec. VP and Therapeutic Head of Gastroenterology | NA |
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